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Poster courtesy of MovieGoods
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Altered States
Locke asks Charlie to stand guard while he goes into the sweat lodge to "talk to the Island."
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CHARLIE: Yeah, I know, I get it. You're
going to go in your little magic hut and I'm going to stand out
here in case you devolve into a monkey.
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In the movie a scientist, with the help of drugs, devolves into a pre-hominid state, or simply put, a monkey.
Quote:
As for the scientist's regression into an ape-like being, the late Dr. Craig Enright, who started me on K (ketamine) while taking a trip with me here by the isolation tank, suddenly "became" a chimp,
jumping up and down and hollering for twenty-five minutes. Watching
him, I was frightened. I asked him later, "Where the hell were you?" He
said, "I became a pre-hominid, and I was in a tree. A leopard was trying to get me. So I was trying to scare him away."
IMDb listing
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Lost at the 
